COBRE in Aging and Regenerative Medicine / Publications
Browse the latest scientific discoveries and advances from our lab.
Impactful advances & discoveries.
The journals of gerontology. Series A, Biological sciences and medical sciences · 2020-11-13
Unique Transcriptome Changes in Peripheral B Cells Revealed by Comparing Age Groups From Naive or Vaccinated Mice, Including snoRNA and Cdkn2a.
Read publicationAmerican journal of physiology. Lung cellular and molecular physiology · 2024-11-23
TGF-β(1) stimulates HDAC4 nucleus-to-cytoplasm translocation and NADPH oxidase 4-derived reactive oxygen species in normal human lung fibroblasts.
Read publicationThe journals of gerontology. Series A, Biological sciences and medical sciences · 2017-10-12
Biological Aging and the Human Gut Microbiota.
Read publicationScientific reports · 2024-11-23
Evaluation of Arteriolar Smooth Muscle Cell Function in an Ex Vivo Microvascular Network Model.
Read publicationExperimental gerontology · 2024-11-23
Adaptation to metabolic dysfunction during aging: Making the best of a bad situation.
Read publicationGeroScience · 2024-11-23
DNA methylation associated with healthy aging of elderly twins.
Read publicationFrontiers in genetics · 2024-11-23
Examination of the Dimensions of Biological Age.
Read publicationTuberculosis (Edinburgh, Scotland) · 2024-11-23
Mucosal-activated invariant T cells do not exhibit significant lung recruitment and proliferation profiles in macaques in response to infection with Mycobacterium tuberculosis CDC1551.
Read publicationRespiratory research · 2024-11-23
Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1.
Read publicationPloS one · 2024-11-23
Cytoskeletal Expression and Remodeling in Pluripotent Stem Cells.
Read publicationGerontology · 2024-11-23
Programmed Cell Death Genes Are Linked to Elevated Creatine Kinase Levels in Unhealthy Male Nonagenarians.
Read publicationJournal of cellular physiology · 2024-11-23
Laser Direct-Write Onto Live Tissues: A Novel Model for Studying Cancer Cell Migration.
Read publicationAdipocyte · 2024-11-23
Human cytomegalovirus infection of human adipose-derived stromal/stem cells restricts differentiation along the adipogenic lineage.
Read publicationLymphatic research and biology · 2024-11-23
Estimation of the Pressure Drop Required for Lymph Flow through Initial Lymphatic Networks.
Read publicationThe journals of gerontology. Series A, Biological sciences and medical sciences · 2017-05-01
Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis.
Read publicationThe Journal of biological chemistry · 2024-11-23
An Intronic Enhancer Element Regulates Angiotensin II Type 2 Receptor Expression during Satellite Cell Differentiation, and Its Activity Is Suppressed in Congestive Heart Failure.
Read publicationThe Journal of biological chemistry · 2024-11-23
Angiotensin type 2 receptor signaling in satellite cells potentiates skeletal muscle regeneration.
Read publicationSkeletal muscle · 2024-11-23
Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function.
Read publicationOncotarget · 2015-02-28
Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival.
Read publicationInterface focus · 2015-04-06
Applications of computational models to better understand microvascular remodelling: a focus on biomechanical integration across scales.
Read publicationBrain and language · 2024-11-23
Speech preparation in adults with persistent developmental stuttering.
Read publicationMolecular therapy : the journal of the American Society of Gene Therapy · 2024-11-23
PAX4 Gene Transfer Induces α-to-β Cell Phenotypic Conversion and Confers Therapeutic Benefits for Diabetes Treatment.
Read publicationTissue engineering. Part B, Reviews · 2024-11-23
Looking Ahead to Engineering Epimorphic Regeneration of a Human Digit or Limb.
Read publicationMicrocirculation (New York, N.Y. : 1994) · 2016-02-23
Macrophages: An Inflammatory Link Between Angiogenesis and Lymphangiogenesis.
Read publicationJournal of diabetes and its complications · 2024-11-23
Vanilloid receptors--do they have a role in whole body metabolism? Evidence from TRPV1.
Read publicationCells, tissues, organs · 2024-11-23
Differentiation patterns of embryonic stem cells in two- versus three-dimensional culture.
Read publicationFrontiers in physiology · 2024-11-23
Vascular islands during microvascular regression and regrowth in adult networks.
Read publicationMicrocirculation (New York, N.Y. : 1994) · 2014-05-21
Targeting pericytes for angiogenic therapies.
Read publicationFrontiers in neuroscience · 2024-11-23
Regulation of neurons in the dorsal motor nucleus of the vagus by SIRT1.
Read publicationMicrocirculation (New York, N.Y. : 1994) · 2014-08-21
VEGF-C induces lymphangiogenesis and angiogenesis in the rat mesentery culture model.
Read publicationJournal of molecular and cellular cardiology · 2024-11-23
Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death.
Read publicationAmerican journal of respiratory cell and molecular biology · 2021-01-06
Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection.
Read publicationMedical & biological engineering & computing · 2024-11-23
The effect of microvascular pattern alterations on network resistance in spontaneously hypertensive rats.
Read publicationBMC physiology · 2024-11-23
Cell proliferation along vascular islands during microvascular network growth.
Read publicationAge (Dordrecht, Netherlands) · 2024-11-23
Association of healthy aging with parental longevity.
Read publicationAmerican journal of physiology. Heart and circulatory physiology · 2024-11-23
An angiogenesis model for investigating multicellular interactions across intact microvascular networks.
Read publicationBiotechnology and bioengineering · 2024-11-23
Shear stress during early embryonic stem cell differentiation promotes hematopoietic and endothelial phenotypes.
Read publicationLymphatic research and biology · 2012-12-10
Relationships between lymphangiogenesis and angiogenesis during inflammation in rat mesentery microvascular networks.
Read publicationTissue engineering. Part A · 2024-11-23
Modulating the physical microenvironment to study regenerative processes in vitro using cells from mouse phalangeal elements.
Read publicationHealthy aging research · 2015-04-23
Quantitative measures of healthy aging and biological age.
Read publicationMethods in molecular biology (Clifton, N.J.) · 2016-11-18
An Ex Vivo Tissue Culture Model for Anti-angiogenic Drug Testing.
Read publicationJournal of leukocyte biology · 2024-11-23
Declining neutrophil production despite increasing G-CSF levels is associated with chronic inflammation in elderly rhesus macaques.
Read publicationFrontiers in oncology · 2024-11-23
Targeting TRAF3IP2 inhibits angiogenesis in glioblastoma.
Read publicationThe EMBO journal · 2024-11-23
Damage-induced regeneration of the intestinal stem cell pool through enteroblast mitosis in the Drosophila midgut.
Read publicationWIREs mechanisms of disease · 2024-11-23
Tumor models in various Drosophila tissues.
Read publicationFrontiers in cell and developmental biology · 2024-11-23
Age-Dependent Changes in Bone Architecture, Patterning, and Biomechanics During Skeletal Regeneration.
Read publicationViruses · 2024-11-23
Gut Microbiome Changes Associated with Epithelial Barrier Damage and Systemic Inflammation during Antiretroviral Therapy of Chronic SIV Infection.
Read publicationAntiviral research · 2024-11-23
Inhibiting cytomegalovirus replication through targeting the host electron transport chain.
Read publicationFrontiers in molecular biosciences · 2024-11-23
A Novel Controlled PTEN-Knockout Mouse Model for Prostate Cancer Study.
Read publicationViruses · 2024-11-23
Metabolic Reprogramming of Glioblastoma Cells during HCMV Infection Induces Secretome-Mediated Paracrine Effects in the Microenvironment.
Read publicationJournal of clinical virology plus · 2024-11-23
SARS-CoV-2 seroprevalence rates of children seeking medical care in Louisiana during the state stay at home order.
Read publicationeLife · 2024-11-23
Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration.
Read publicationFrontiers in immunology · 2024-11-23
Impact of SIV infection on mycobacterial lipid-reactive T cell responses in Bacillus Calmette-Guérin (BCG) inoculated macaques.
Read publicationBrain, behavior, and immunity · 2024-11-23
Intermittent systemic exposure to lipopolysaccharide-induced inflammation disrupts hippocampal long-term potentiation and impairs cognition in aging male mice.
Read publicationCommunications biology · 2024-11-23
The dynamics of γδ T cell responses in nonhuman primates during SARS-CoV-2 infection.
Read publicationBiochimica et biophysica acta. Reviews on cancer · 2024-11-23
Unfolded protein response and angiogenesis in malignancies.
Read publicationCancers · 2024-11-23
A Novel Strategy to Model Age-Related Cancer for Elucidation of the Role of Th17 Inflammaging in Cancer Progression.
Read publicationJournal of biomechanics · 2024-11-23
Evaluating differences in Young's Modulus of regenerated and uninjured mouse digit bone through microCT density-based calculation and nanoindentation testing.
Read publicationFrontiers in immunology · 2024-11-23
Dysregulation of IL-17/IL-22 Effector Functions in Blood and Gut Mucosal Gamma Delta T Cells Correlates With Increase in Circulating Leaky Gut and Inflammatory Markers During cART-Treated Chronic SIV Infection in Macaques.
Read publicationCurrent clinical microbiology reports · 2024-11-23
Host Mitochondrial Requirements of Cytomegalovirus Replication.
Read publicationMolecular biology of the cell · 2024-11-23
SET levels contribute to cohesion fatigue.
Read publicationThe journals of gerontology. Series A, Biological sciences and medical sciences · 2024-11-23
An elevation of resting metabolic rate with declining health in nonagenarians may be associated with decreased muscle mass and function in women and men, respectively.
Read publicationTissue engineering. Part A · 2024-11-23
Fluid shear stress pre-conditioning promotes endothelial morphogenesis of embryonic stem cells within embryoid bodies.
Read publicationPsychophysiology · 2024-11-23
Cortical potentials in an auditory oddball task reflect individual differences in working memory capacity.
Read publicationJournal of neurophysiology · 2024-11-23
Reduced GABAergic inhibition of kidney-related PVN neurons in streptozotocin-treated type 1 diabetic mouse.
Read publicationPloS one · 2024-11-23
Detecting splicing variants in idiopathic pulmonary fibrosis from non-differentially expressed genes.
Read publicationBiochemical and biophysical research communications · 2024-11-23
Computational proteome-wide screening predicts neurotoxic drug-protein interactome for the investigational analgesic BIA 10-2474.
Read publicationThe American journal of the medical sciences · 2016-10-01
Mechanisms of Cachexia in Chronic Disease States.
Read publicationMethods in molecular biology (Clifton, N.J.) · 2017-01-01
Applying Shear Stress to Pluripotent Stem Cells.
Read publicationFrontiers in neuroscience · 2024-11-23
Rapid cortical dynamics associated with auditory spatial attention gradients.
Read publicationGenes & development · 2015-06-01
Mechanism of regulation of 'chromosome kissing' induced by Fob1 and its physiological significance.
Read publicationAging cell · 2024-11-23
Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1.
Read publicationPloS one · 2024-11-23
An ex vivo model for anti-angiogenic drug testing on intact microvascular networks.
Read publicationJournal of vascular research · 2024-11-23
Pericyte dynamics during angiogenesis: new insights from new identities.
Read publicationTissue engineering. Part A · 2014-12-20
Correlating the effects of bone morphogenic protein to secreted soluble factors from fibroblasts and mesenchymal stem cells in regulating regenerative processes in vitro.
Read publicationRespiratory research · 2024-11-23
Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.
Read publicationScientific reports · 2024-11-23
Lack of vimentin impairs endothelial differentiation of embryonic stem cells.
Read publicationGenetics · 2024-11-23
Identification of the Target of the Retrograde Response that Mediates Replicative Lifespan Extension in Saccharomyces cerevisiae.
Read publicationClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024-11-23
Cortical activity during cued picture naming predicts individual differences in stuttering frequency.
Read publicationThe Journal of biological chemistry · 2024-11-23
Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction.
Read publicationPhysiological reports · 2016-07-04
Lysophosphatidic acid does not cause blood/lymphatic vessel plasticity in the rat mesentery culture model.
Read publicationeLife · 2024-11-23
Nerve growth factor receptor negates the tumor suppressor p53 as a feedback regulator.
Read publicationBiogerontology · 2024-11-23
Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians.
Read publicationIntegrative biology : quantitative biosciences from nano to macro · 2024-11-23
Printing cancer cells into intact microvascular networks: a model for investigating cancer cell dynamics during angiogenesis.
Read publicationScientific reports · 2024-11-23
Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism.
Read publicationJournal of biomechanical engineering · 2017-10-01
Biaxial Mechanical Assessment of the Murine Vaginal Wall Using Extension-Inflation Testing.
Read publicationFrontiers in genetics · 2024-11-23
Metabolic and Genetic Markers of Biological Age.
Read publicationGeroScience · 2024-11-23
The frailty index outperforms DNA methylation age and its derivatives as an indicator of biological age.
Read publicationJournal of visualized experiments : JoVE · 2024-11-23
An Ex Vivo Method for Time-Lapse Imaging of Cultured Rat Mesenteric Microvascular Networks.
Read publicationThe Prostate · 2024-11-23
Targeting Th17-IL-17 Pathway in Prevention of Micro-Invasive Prostate Cancer in a Mouse Model.
Read publicationDevelopmental biology · 2024-11-23
Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner.
Read publicationAmerican journal of physiology. Heart and circulatory physiology · 2024-11-23
Aging is associated with impaired angiogenesis, but normal microvascular network structure, in the rat mesentery.
Read publicationAmerican journal of clinical and experimental urology · 2024-11-23
Interleukin-17 promotes metastasis in an immunocompetent orthotopic mouse model of prostate cancer.
Read publicationPloS one · 2024-11-23
Actin and myosin II modulate differentiation of pluripotent stem cells.
Read publicationBioEssays : news and reviews in molecular, cellular and developmental biology · 2024-11-23
Multitasking Ska in Chromosome Segregation: Its Distinct Pools Might Specify Various Functions.
Read publicationBiomechanics and modeling in mechanobiology · 2024-11-23
Evaluation of microstructurally motivated constitutive models to describe age-dependent tendon healing.
Read publicationScientific reports · 2024-11-23
Marked bias towards spontaneous synaptic inhibition distinguishes non-adapting from adapting layer 5 pyramidal neurons in the barrel cortex.
Read publicationArthritis & rheumatology (Hoboken, N.J.) · 2024-11-23
The Antiretroviral Agent Nelfinavir Mesylate: A Potential Therapy for Systemic Sclerosis.
Read publicationScientific reports · 2024-11-23
Marked bias towards spontaneous synaptic inhibition distinguishes non-adapting from adapting layer 5 pyramidal neurons in the barrel cortex.
Read publicationScience (New York, N.Y.) · 2024-11-23
Mitotic transcription and waves of gene reactivation during mitotic exit.
Read publicationThe Journal of cell biology · 2024-11-23
SET binding to Sgo1 inhibits Sgo1-cohesin interactions and promotes chromosome segregation.
Read publicationJournal of applied physiology (Bethesda, Md. : 1985) · 2024-11-23
Angiotensin II suppresses autophagy and disrupts ultrastructural morphology and function of mitochondria in mouse skeletal muscle.
Read publicationAmerican journal of medical genetics. Part A · 2024-11-23
Exome sequencing reveals a novel COL2A1 mutation implicated in multiple epiphyseal dysplasia.
Read publicationBiology of reproduction · 2019-04-01
Disruption of ubiquitin specific protease 26 gene causes male subfertility associated with spermatogenesis defects in mice†.
Read publicationJournal of biomechanical engineering · 2019-02-01
Effects of Elastase Digestion on the Murine Vaginal Wall Biaxial Mechanical Response.
Read publicationBiogerontology · 2024-11-23
Dual roles of mitochondrial fusion gene FZO1 in yeast age asymmetry and in longevity mediated by a novel ATG32-dependent retrograde response.
Read publicationGeroScience · 2024-11-23
A novel high-throughput assay for respiration in isolated brain microvessels reveals impaired mitochondrial function in the aged mice.
Read publicationFrontiers in immunology · 2024-11-23
Beneficial Effects of Human Anti-Interleukin-15 Antibody in Gluten-Sensitive Rhesus Macaques with Celiac Disease.
Read publicationEssays in biochemistry · 2020-09-04
Functioning mechanisms of Shugoshin-1 in centromeric cohesion during mitosis.
Read publicationNature communications · 2024-11-23
Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins.
Read publicationScientific reports · 2024-11-23
Comparison of Biaxial Biomechanical Properties of Post-menopausal Human Prolapsed and Non-prolapsed Uterosacral Ligament.
Read publicationNeurobiology of aging · 2024-11-23
Neural correlates of auditory sensory memory dynamics in the aging brain.
Read publicationGeroScience · 2024-11-23
Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells.
Read publicationScientific reports · 2024-11-23
Sirtuin 3 deficiency does not impede digit regeneration in mice.
Read publicationJournal of virology · 2024-11-23
Human Cytomegalovirus Alters Host Cell Mitochondrial Function during Acute Infection.
Read publicationNeurobiology of aging · 2024-11-23
Reduced sensory-evoked structural plasticity in the aging barrel cortex.
Read publicationJournal of the mechanical behavior of biomedical materials · 2024-11-23
Bayesian inference of constitutive model parameters from uncertain uniaxial experiments on murine tendons.
Read publicationThe Journal of cell biology · 2024-11-23
SET binding to Sgo1 inhibits Sgo1-cohesin interactions and promotes chromosome segregation.
Read publicationCerebral cortex (New York, N.Y. : 1991) · 2020-03-21
Dendritic Spine Density and Dynamics of Layer 5 Pyramidal Neurons of the Primary Motor Cortex Are Elevated With Aging.
Read publicationScientific reports · 2024-11-23
LTA1 is a safe, intranasal enterotoxin-based adjuvant that improves vaccine protection against influenza in young, old and B-cell-depleted (μMT) mice.
Read publicationThe Prostate · 2024-11-23
CD4(+) T helper 17 cell response of aged mice promotes prostate cancer cell migration and invasion.
Read publication